Search genetic and rare diseases information center gard. If you have problems viewing pdf files, download the latest version of adobe reader. Genetic and rare diseases information center gard po box 8126, gaithersburg, md 208988126 toll free. To test the effect of maternal seizure disorders on prenatal structural development, the mouse neurological mutant quaking qk was used. A case of prenatal diagnosis of fetal hydantoin syndrome by ultrasound. Fetal hydantoin syndrome is a disorder that is caused by exposure of a fetus to phenytoin, a drug commonly prescribed for epilepsy. Pdf a case of prenatal diagnosis of fetal hydantoin. Sfa alexandra almeida 12 14 epidemiologia prevalencia na europa.
Fetal hydantoin syndrome fhs is a set of disruptions occasionally present in fetuses exposed in utero to phenytoin or other anticonvulsants. Fetalalcoholic syndrome, alcoholism, evaluation, intervention. Sindrome por hidantoina fetal sintomas, causas, medicamentos, diagnostico, y diagnosticos erroneos. Not all infants exposed to phenytoin will be affected with the disorder. Incidence of fetal alcohol syndrome and prevalence of alcoholrelated neurodevelopmental disorder. Fetal hydantoin syndrome is a drugrelated embryofetopathy that can occur when an embryofetus is exposed to the anticonvulsant drug. Fetal hydantoin syndrome is a drugrelated embryofetopathy that can occur when an embryofetus is exposed to. Search genetic and rare diseases information center. Fetal hydantoin syndrome is a characteristic pattern of mental and physical birth defects that results from maternal use of the antiseizure anticonvulsant drug phenytoin dilantin during pregnancy. Administering phenytoin in the drinking water of females homozygous for the quaking allele reduced the frequency of tonic. As atitudes dos professores face a sindrome alcoolica fetal. Fetal hydantoin syndrome nord national organization for. The range and severity of associated abnormalities will vary greatly from one infant to another.
For language access assistance, contact the ncats public information officer. Fetal alcohol syndrome and fetal alcohol spectrum disorders. Symptoms in affected individuals may include abnormalities of the skull and facial features, growth deficiencies, underdeveloped nails of the fingers and toes, andor mild developmental delays. Fetal hydantoin syndrome genetic and rare diseases. Phenytoin is presumed to disrupt normal development of some fetuses when administered during pregnancy. A case of prenatal diagnosis of fetal hydantoin syndrome. In the 60s, effects attributed to this medication were grouped into a somewhat recognizable pattern of anomalies briggs et al. Supreme court of washington, jaunary 6, 1983 98 wash. Fetal alcohol syndrome fas and fetal alcohol spectrum disorders fasd result from intrauterine exposure to alcohol and are the most common nonheritable causes of intellectual disability.